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Probiotics are officially defined as:
A more common definition is:
The word ‘probiotic' is derived from the Greek words for ‘Pro Life' and has been defined in many different ways during the last decades. In all cases, however, it designated a bacterial product, which would benefit the health of the host.
The three main aspects of the definition are:
This means that probiotic bacteria should be resistant against acid (stomach), bile, capable of growing under anaerobic conditions and be non-toxic. These criteria limit the number of bacterial species and strains to the following groups of bacteria: Lactobacillus, Streptococcus and Bifidobacterium species, although some other species can be used in some cases (such as yeasts and Bacillus species in animal nutrition). All three genera are part of the lactic acid bacteria and are naturally present in the intestine as well as in many fermented (mainly acid) dairy products.
Probiotics are claimed to have beneficial effects on the host (human or animal) health. The following claims have been attributed to strains of lactobacilli and bifidobacteria:
However, most of these claims are very vague and in most cases not proven scientifically. Only a few proper scientific studies with normal adult volunteers have been carried out, and only for a few strains. For only a few strains some of the above claims have been verified. Reduction of diarrhoea, improved digestion of lactose, reduced constipation and beneficial effects on Candida have been scientifically proven for a number of strains. For most other claims there is no or very little scientific evidence.
For each individual strain (and product) the claims should be properly investigated, which, unfortunately, has not been done for many probiotics and probiotic products, especially the lyophilised powders, pills and capsules (food supplements).
Even if there is scientific proof that a certain strain has probiotic characteristics, it does not mean that the strain is effective in every person, as each person has his/her own intestinal flora, which may limit the effectiveness of a probiotic product.
Whether probiotic products are effective is therefore very hard to predict. There are many products on the market which are most likely not effective at all. Two recent studies, in the Netherlands and the UK, have shown that in many products (mainly food supplements) no or very few living bacteria are present, which thus are certainly ineffective. In the Dutch study, 80% of the products showed wrong information on the label. A short own survey of the Wageningen University, showed similar data on label information for non-Dutch products.
The EU (and US) food law describes that all ingredients should be properly listed. However, for many probiotic products this seems not to be the reality. As probiotic effects are strain dependent, as described above, it is necessary to mention the proper bacterial name and strain. As bacterial nomenclature often changes, it is necessary to mention the strain numbers/designation, as these do not change. Only by using the strain number the consumer, or the dietician or physician, can verify the (claimed) effects of the bacteria and thus the product.
If the label shows obsolete or wrong names, it can reasonably be assumed that the producer is not aware of the scientific literature of the last decades.
When in doubt about the product, always ask the producer for the strain numbers and scientific references on the claims. Be aware of advertising and ‘joyriding', see below. Reliable producers can easily provide this information. When the information can not be provided, be sceptical on the product !
When the label states the presence of the following species, the producer is not aware of current scientific data:
Lactobacillus bifidus; this name became obsolete in 1969 (!) and may not be used since. Producers claiming the presence of this ‘species', therefore are not up-to-date. The name was used for what is now the whole genus Bifidobacterium, with 22 different species. The name has as much value as stating that a dairy product contains milk. Or, in the car analogy, the garage states that he sells a German car, which gives no information at all on the type and characteristics.
Streptococcus faecium ; this name became obsolete in the early 1980s and may not be used since. The correct name is Enterococcus faecium. As this species is also a known pathogen, it is necessary that the strain number and name are properly used.
Fantasy names are names observed on ‘probiotic' products, but that do not exist and thus are illegally used.
Lactobacillus caucasicus; another fantasy name. It is totally unknown which bacterium is used in products with this ‘strain'.
Any health benefits of products with these two ‘species', are not to be expected. Any literature on these bacteria can not be considered reliable, as no microbiological or medical journal would accept data on a non existing species.
Lactobacillus acidophilus casei . This should be either a Lb. acidophilus, or a Lb. casei . It is like selling a Volkswagen Golf Passat.
Verified probiotic strains:
Lactobacillus casei Shirota (or LCS), from Yakult and used in the product of the same name.
Verified non-probiotic strains
The following organisms are not probiotic, as they do not survive the stomach and bile and will thus not be alive in the intestine:
The yoghurt bacteria Lactobacillus delbrueckii ssp bulgaricus and Streptococcus salivarius ssp thermophilus, Lactobacillus helveticus
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